Pharmaceutical Pollution: What it is, and How Pharmaceutical Pollution Threatens Your Health
by www.SixWise.com
Americans are prescribed millions of doses of prescription 
     drugs every year. Livestock are given millions more. But after 
     the pill has been swallowed or the injection taken, the active 
     components of the drugs do not become inert or completely 
     absorbed by the body. 
      
      
       | 
 One study found that 80 percent of streams tested contained 
        antibiotics, steroids, synthetic hormones or other common 
        drugs. | 
      
      Far from disappearing, the drugs are excreted and now, scientists 
     are finding, prescription drugs are showing up in our ground 
     water, soil, waterways and even our drinking water. That's 
     because our conventional sewage treatments may not be looking 
     for drugs, and certainly don't always remove them.
      Adding to the problem are prescription drugs that aren't 
     used, then are flushed down the toilet or deposited in landfills 
     -- ultimately ending up in the environment.
      This so-called "pharmaceutical pollution" could 
     have major implications on wildlife, agriculture and humans 
     -- yet is only beginning to be studied.
      "This is an important new research area," said 
     A. Lynn Roberts, leader of a Johns Hopkins team that began 
     a study to determine the scope of pharmaceutical pollution 
     in the United States. Roberts continued:
      "Over the past few years, scientists in Europe have 
     found pharmaceuticals in natural waterways, sewage treatment 
     effluents and even in drinking water. Yet until this year 
     [2003] there have been virtually no scientific studies examining 
     this issue in the United States. It's important that we begin 
     to look at this because there are many ways in which pharmaceuticals 
     in the environment could produce undesirable effects on aquatic 
     organisms or even humans."
      How Widespread is the Problem?
      Current estimates are still being gathered, but a study conducted 
     in 1999-2000 by the U.S. Geological Survey (USGS) found that 
     most waterways contain at least some antibiotics, steroids, 
     synthetic hormones or other common drugs. Out of 139 streams 
     in 30 states, they found:
      
     - 
       About 80 percent contained trace amounts of contaminants 
- 
       Half the streams contained seven or more chemical compounds 
        
- 
        One-third of the streams contained 10 or more compounds 
-  One water sample contained 38 chemicals
"We're not talking about rampant dumping," said 
     one USGS survey official. "We're looking at the effect 
     of normal existing usage for these different chemicals."
      Just how many drugs are we using currently? A lot. Here are 
     some statistics just for antibiotics (not including any other 
     types of drugs):
      
      When a drug is taken, experts say up to 90 percent may be 
     excreted back into the environment, unchanged. 
      What kinds of drugs -- and to what extent -- are currently 
     out there is anyone's guess. Padma Venkatraman, a postdoctoral 
     fellow at Johns Hopkins who is part of the research team, 
     believes the drugs most likely to be found at "toxicologically 
     significant levels" include:
      
     -  
       Antidepressants 
-  
        Anti-convulsants 
-  
        Anti-cancer drugs 
-  
        Anti-microbials  
"We're trying to make an intelligent guess as to what's 
     out there in the environment and what's probably toxic," 
     Venkatraman said.
      Antibiotic-Resistant Bacteria on the Rise
      
      
       | 
 Up to 90 percent of a drug you consume may be excreted 
        -- unchanged. | 
      
      Just one problem stemming from pharmaceutical pollution is 
     antibiotic-resistant bacteria. When drugs are excreted in 
     waste, the compounds linger in the environment. In the case 
     of livestock waste, the antibiotic-laced manure is spread 
     directly onto farm crops as fertilizer. From there it may 
     run off into nearby streams.
      The result is that bacteria is able to mutate into strains 
     that are resistant to the widely spread antibiotics, paving 
     the way for infections that cannot be easily cured. 
      According to the Centers for Disease Control and Prevention, 
     about 2 million people in hospitals get infections each year, 
     which cause 90,000 deaths. Of these, more than 70 percent 
     of the bacteria that causes these infections are resistant 
     to at least one common antibiotic that is typically used to 
     treat them.
      Health Problems Remain a Mystery
      "Little is known about the potential interactive effects" 
     from complex mixtures of waste contaminants in the environment, 
     according to USGS. 
      For instance, Roberts pointed out that antidepressants work 
     by altering levels of serotonin. However, serotonin causes 
     many aquatic creatures to spawn. The result could be that 
     prescription drugs may alter breeding cycles in the wild. 
     Further, drugs can have major impacts on developing fetuses 
     in humans. If small amounts showed up in drinking water, it 
     could cause birth defects or other problems.
      "Pharmaceuticals have high biological activity," 
     Roberts said. "We may be able to tolerate them for a 
     short period of time, but that doesn't mean they won't hurt 
     us -- or developing fetuses or aquatic organisms -- at higher 
     concentrations or over a long period of time."
      There is good news, and that is that attention to this issue 
     is growing, and so is the drive to find out just what types 
     of problems may be occurring. 
      The USGS agrees, stating in their report that "protecting 
     the integrity of our water resources is one of the most essential 
     environmental issues of the 21st century."
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